In the world of biotechnology and life sciences, perfusion cell culture is a process that has been gaining traction in recent years. Put simply, this type of cell culture is a method used to grow cells under continuous flow conditions. It’s ideal for applications that require continuous production of proteins over an extended period of time, such as those found in pharmaceutical manufacturing and bioprocessing.

Let’s take a look at some of the benefits associated with this method of cell culture.

Cost Savings

Perfusion cell culture can save you money by improving the efficiency of your bioprocesses. This type of system reduces the need to harvest cells or replenish media on a regular basis, which means that fewer resources are needed over time. Additionally, because continuous flow systems reduce waste, there is less potential for contamination and loss due to spillage or other environmental factors. The end result? A reduction in both material costs and labor costs associated with your bioprocesses.

Flexibility

Another benefit of using perfusion cell culture is its flexibility. Unlike traditional batch systems where cells are grown in discrete batches, this system allows you to adjust parameters such as feed rate, nutrient concentrations, and temperature on an ongoing basis without having to stop production altogether. This makes it easier to scale up or down your processes quickly and efficiently as needed, which is a valuable capability when dealing with unpredictable demand fluctuations or market changes.

Product Quality Control

Finally, another advantage of using perfusion cell cultures is improved product quality control. Because this type of system allows for precise monitoring and control over key parameters such as oxygen levels and nutrient concentrations throughout the growth cycle, you can ensure consistent product quality from batch to batch regardless of environmental factors or fluctuations in demand for your products.